O'Hara made her professional acting debut in 1974 with the celebrated Second City improvisational company. Subsequently, she and a number of her Second City colleagues created the Emmy Award-winning television series SCTV, on which O'Hara appeared for 5 years.

O'Hara made her feature film debut in After Hours. Other film credits include Home Alone, Home Alone 2: Lost in New York, Heartburn, Beetlejuice, The Nightmare Before Christmas, Dick Tracy, Wyatt Earp, Tall Tales and Last Of The High Kings.

More recently, O'Hara has starred in such films as Waiting For Guffman, Home Fries and The Last Night. She also received a Genie award for her most recent film, The Life Before This.

In addition to appearing on such television series as The Larry Sanders Show, The Outer Limits and Saturday Night Live, as guest host, O'Hara has also directed The Outer Limits and HBO's Dream On series.

Credit: cinema.com